SCHEMBL87485

SCHEMBL87485

O=C(O)c1ccc2c(c1C(=O)O)Oc1ccccc1O2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.45
ALOX5 P09917 3/20 0.41
ALDH1A1 P00352 4/20 0.40
AHR P35869 2/20 0.40
ALOX15 P16050 1/20 0.40
AKR1C3 P42330 1/20 0.37
CDC25A P30304 1/20 0.37
CDC25B P30305 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP1A2 P05177 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
HMGB1 P09429 1/20 0.35
HPGD P15428 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA7 P43166 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9721062 0.91 CYP1A2 (0.42) CYP2C9ALOX5ALDH1A1ALOX15AKR1C3
SCHEMBL7023823 0.86 HSD17B10 (0.37) CYP2C9ALOX5ALDH1A1AHRALOX15
SCHEMBL6445212 0.79 CYP2C9 (0.53) CYP2C9ALOX5ALDH1A1AHRALOX15
Phthalic Acid SCHEMBL28481098 0.76 ALDH1A1 (0.70) CYP2C9ALOX5ALDH1A1ALOX15AKR1C3
SCHEMBL83906 0.73 MAOA (0.48) CYP2C9ALOX5ALDH1A1ALOX15HSD17B10
SCHEMBL6704014 0.73 ALOX5 (0.44) CYP2C9ALOX5ALDH1A1ALOX15AKR1C3
SCHEMBL8422539 0.73 WDR5 (0.43) CYP2C9ALDH1A1ALOX15CDC25BCYP1A2
SCHEMBL6530620 0.72 ALDH1A1 (0.50) CYP2C9ALOX5ALDH1A1ALOX15AKR1C3
SCHEMBL87644 0.72 CYP2C9 (0.40) CYP2C9ALOX5ALDH1A1ALOX15AKR1C3
SCHEMBL28596619 0.72 P2RX4 (0.44) CYP2C9ALOX5ALDH1A1ALOX15SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-1347015-B1 Resin composition and molded product DAINIPPON INK & CHEMICALS (JP) 2005-09-21 EP disclosed
US-6677406-B2 Heat resistance; impact strength; dimensional stability; molding materials DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-01-13 US disclosed
US-20030187150-A1 Resin composition and molded product DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-10-02 US disclosed
EP-1347015-A1 Resin composition and molded product DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP2C9 2591/4885ALOX5 899/4885ALDH1A1 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.