SCHEMBL65490

SCHEMBL65490

CC(C)(C)OC(=O)N1CCCC[C@H]1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.55
RAB9A P51151 1/20 0.51
NPC1 O15118 1/20 0.49
LMNA P02545 2/20 0.49
CYP2C19 P33261 1/20 0.49
ALDH1A1 P00352 2/20 0.48
NPSR1 Q6W5P4 1/20 0.47
UCHL1 P09936 1/20 0.45
HPGD P15428 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65491 1.00 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL77858 1.00 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL222955 0.98 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL5898691 0.98 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL18358031 0.98 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL6219872 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL85536 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67045 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67044 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL27877016 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 905 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977978-A Catalytic synthesis method of chiral pyrazolo hydro-pyran compound 中国海洋大学 2025-05-13 CN claimed
CN-118852326-A PROTAC compound for targeted degradation of PI3K 110 beta and preparation method and application thereof 河南大学 2024-10-29 CN claimed
CN-118255837-A Method for synthesizing illegal stand 苏州特瑞药业股份有限公司 2024-06-28 CN claimed
CN-115650903-B Preparation method of initial amino acid Boc-Pip (Fmoc) -OH 苏州天马医药集团天吉生物制药有限公司 2024-05-28 CN claimed
CN-115650903-A Preparation method of initial amino acid Boc-Pip (Fmoc) -OH 苏州天马医药集团天吉生物制药有限公司 2023-01-31 CN claimed
CN-101168514-B Practical synthesis method for alpha-aminosuberate and alpha-amino suberic acid monoester with optical activity SHANGHAI YAOMING KANGDE NEW MEDICINE DEVELOPMENT CO., LTD. (CN) 2011-12-07 CN claimed
CN-101168514-A Practical synthesis method for alpha-aminosuberate and alpha-amino suberic acid monoester with optical activity SHANGHAI PHARMATECH CO LTD (CN) 2008-04-30 CN claimed
CN-122036596-A N- (2 ',6' -xylyl) -2-piperidine carboxamide derivative and application thereof 中国药科大学 2026-05-15 CN disclosed
WO-2026101698-A1 HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF PROTAGONIST THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
US-20260125375-A1 SUBSTITUTED 1H-PYRAZOLO-PYRIDINE AND -PYRIMIDINE COMPOUNDS PFIZER INC. (US) 2026-05-07 US disclosed
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS GIVAUDAN SA (CH) 2026-04-16 US disclosed
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE BIOHAVEN THERAPEUTICS LTD (US) 2026-04-02 US disclosed
WO-1994007858-A1 1-(2-OXO-ACETYL)-PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES AS MULTI-DRUG-RESISTENT CANCER CELL SENSITIZERS VERTEX PHARMACEUTICALS INCORPORATED (US) 1994-04-14 WO disclosed
US-5250517-A Hypotensive and cardiotonic agents; cardiac insufficiency HOFFMANN-LA ROCHE INC. (US) 1993-10-05 US disclosed
US-5235066-A FK-506 type macrolide intermediate MERCK & CO., INC. (US) 1993-08-10 US disclosed
US-5164525-A SYNTHETIC PROCESS FOR FK-506 TYPE MACROLIDE INTERMEDIATES MERCK & CO., INC. (US) 1992-11-17 US disclosed
EP-0488301-A1 New benzopyran compounds with pharmacological activity J. URIACH & CIA. S.A. (ES) 1992-06-03 EP disclosed
EP-0405994-A2 Synthetic process for FK-506 type macrolide intermediates MERCK & CO. INC. (US) 1991-01-02 EP disclosed
EP-0310918-A2 Peptide-like amino-acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS TRPM8, TRPM7, TRPM5 HSD17B10 3385/4885SMN1; SMN2 2680/4885RAB9A 1602/4885
US-20260091024-A1 PRODRUGS OF RILUZOLE AND THEIR METHOD OF USE IL6ST, GFRA3, GFRA1 HSD17B10 342/4885SMN1; SMN2 36/4885RAB9A 893/4885
US-20260125375-A1 SUBSTITUTED 1H-PYRAZOLO-PYRIDINE AND -PYRIMIDINE COMPOUNDS CCR1, CCR6, CCRL2 HSD17B10 2918/4885SMN1; SMN2 3318/4885RAB9A 1097/4885
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR HSD17B10 1168/4885SMN1; SMN2 881/4885RAB9A 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.