SCHEMBL65491

SCHEMBL65491

CC(C)(C)OC(=O)N1CCCCC1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.55
RAB9A P51151 1/20 0.51
NPC1 O15118 1/20 0.49
LMNA P02545 2/20 0.49
CYP2C19 P33261 1/20 0.49
ALDH1A1 P00352 2/20 0.48
NPSR1 Q6W5P4 1/20 0.47
UCHL1 P09936 1/20 0.45
HPGD P15428 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL77858 1.00 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL65490 1.00 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL222955 0.98 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL5898691 0.98 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL18358031 0.98 HSD17B10 (0.62) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL6219872 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL85536 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67045 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL67044 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA
SCHEMBL27877016 0.95 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744549-B Betulic acid derivant and preparation method thereof and the application in antitumor drug is prepared 华东师范大学 2017-03-29 CN claimed
CN-106220607-A A kind of synthetic method of S 3 (piperidines 2 base) azetidine 3 alcohol 成都百事兴科技实业有限公司 2016-12-14 CN claimed
CN-104744549-A Betulinic acid derivative as well as preparation method and application thereof in preparing antineoplastic drugs UNIV EAST CHINA NORMAL 2015-07-01 CN claimed
CN-101168514-B Practical synthesis method for alpha-aminosuberate and alpha-amino suberic acid monoester with optical activity SHANGHAI YAOMING KANGDE NEW MEDICINE DEVELOPMENT CO., LTD. (CN) 2011-12-07 CN claimed
CN-101168514-A Practical synthesis method for alpha-aminosuberate and alpha-amino suberic acid monoester with optical activity SHANGHAI PHARMATECH CO LTD (CN) 2008-04-30 CN claimed
EP-1581525-A2 COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS AstraZeneca AB (SE) 2005-10-05 EP claimed
US-20040106607-A1 New compounds ASTRAZENECA AB AND NPS PHARMACEUTICALS, INC. 2004-06-03 US claimed
WO-2004014902-A2 COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS ASTRAZENECA AB (SE) 2004-02-19 WO claimed
US-12629359-B2 Structural analogues of methylphenidate as Parkinson's disease-modifying agents UNIVERSITA' DEGLI STUDI DI BRESCIA (IT) 2026-05-19 US disclosed
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
EP-4463455-B1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS SUVEN LIFE SCIENCES LTD (IN) 2026-04-29 EP disclosed
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS GIVAUDAN SA (CH) 2026-04-16 US disclosed
EP-0099056-B1 N-ACYL DERIVATIVES OF DIPEPTIDES, THEIR MANUFACTURE AND USE IN TREATING DISEASES, AND MEANS THEREFOR BASF Aktiengesellschaft (DE) 1987-09-30 EP disclosed
EP-0186292-A2 Tripeptides and sweetening agents containing the same AJINOMOTO CO., INC. (JP) 1986-07-02 EP disclosed
US-4576749-A 3-Acylamino-1-carboxymethylaminocarbonyl-2-azetidinones E. R. SQUIBB & SONS, INC. (US) 1986-03-18 US disclosed
EP-0099056-A2 N-acyl derivatives of dipeptides, their manufacture and use in treating diseases, and means therefor BASF Aktiengesellschaft (DE) 1984-01-25 EP disclosed
US-4225495-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1980-09-30 US disclosed
US-4192945-A Process for preparing proline and homoproline derivatives E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS TRPM8, TRPM7, TRPM5 HSD17B10 3385/4885SMN1; SMN2 2680/4885RAB9A 1602/4885
US-20040106607-A1 New compounds MTX1, MLX, TPX2 HSD17B10 3279/4885SMN1; SMN2 2508/4885RAB9A 959/4885
US-12629359-B2 Structural analogues of methylphenidate as Parkinson's disease-modifying agents SNCA, SYNJ1, PARK7 HSD17B10 2720/4885SMN1; SMN2 64/4885RAB9A 842/4885
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR HSD17B10 1168/4885SMN1; SMN2 881/4885RAB9A 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.