Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702291 | 0.78 | — | — | |
| SCHEMBL6701771 | 0.77 | HTT (0.31) | MAPTTSHRHTT | |
| SCHEMBL6703661 | 0.73 | MEN1 (0.32) | MAPTHTT | |
| SCHEMBL7092958 | 0.72 | PDE4A (0.34) | MAPT | |
| SCHEMBL29403637 | 0.72 | TRPV4 (0.36) | MAPT | |
| SCHEMBL6704409 | 0.72 | MAPT (0.32) | MAPTTSHRHTT | |
| SCHEMBL1008694 | 0.72 | TRPV4 (0.36) | MAPT | |
| SCHEMBL6700564 | 0.71 | — | — | |
| Diethylamine SCHEMBL7031731 | 0.71 | TRPV4 (0.34) | MAPTTSHR | |
| SCHEMBL28751612 | 0.70 | ALDH1A1 (0.34) | MAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |