Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704413 | 0.77 | MAPT (0.31) | HTTMAPTTSHR | |
| SCHEMBL6702291 | 0.77 | — | — | |
| SCHEMBL6701763 | 0.75 | TRPV4 (0.32) | HTTMAPTTSHR | |
| SCHEMBL6703807 | 0.72 | PLTP (0.39) | HTTMAPTTSHR | |
| SCHEMBL6702286 | 0.71 | MAPT (0.32) | HTTMAPTTSHR | |
| SCHEMBL6698972 | 0.71 | TRPV4 (0.34) | MAPTTSHR | |
| SCHEMBL6700564 | 0.70 | — | — | |
| SCHEMBL6703571 | 0.67 | — | — | |
| SCHEMBL6703731 | 0.67 | MAPT (0.34) | HTTMAPT | |
| SCHEMBL6704672 | 0.66 | TSHR (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |