Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702291 | 0.89 | — | — | |
| SCHEMBL6703571 | 0.80 | — | — | |
| SCHEMBL6705261 | 0.78 | MAPT (0.30) | MAPT | |
| SCHEMBL6704674 | 0.74 | MAPT (0.31) | MAPT | |
| SCHEMBL27598406 | 0.72 | PLTP (0.41) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6704413 | 0.72 | MAPT (0.31) | MAPT | |
| SCHEMBL27598408 | 0.71 | MAPT (0.35) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL7092957 | 0.71 | TRPV4 (0.36) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6701383 | 0.67 | SAE1 (0.34) | PDE4BMAPTKMT2AALDH1A1 | |
| SCHEMBL6703128 | 0.65 | GPR35 (0.47) | MAPTDCTPP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |