Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | ITGAL | P20701 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL11219857 | 0.70 | AHR (0.77) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL27263404 | 0.70 | AHR (0.77) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL27468909 | 0.67 | AHR (0.71) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL6692522 | 0.67 | TRPA1 (0.42) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28419364 | 0.66 | AHR (0.94) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL3538342 | 0.66 | AHR (0.94) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL28180904 | 0.66 | AHR (0.94) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL4364385 | 0.66 | AHR (0.94) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL29418271 | 0.66 | AHR (0.94) | AHRTRPA1CA1CA2ITGB2 | |
| Indole SCHEMBL2071445 | 0.66 | TRPA1 (0.68) | AHRTRPA1CA1CA2ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004534034-A | New interleukin-12 8 receptor antagonist 5 syano -1h-1,2,4-triazole-1-ethanol indole derivative | ラボラトワール フルニエ エス・アー | 2004-11-11 | — | — | JP | disclosed |