Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indole SCHEMBL11219857 | 0.71 | AHR (0.77) | TRPA1CA1CA2ITGB2ICAM1 | |
| SCHEMBL16181410 | 0.70 | HTT (0.42) | HDAC1HDAC6NPC1MTORALDH1A1 | |
| Biphenyl SCHEMBL11831610 | 0.69 | AHR (0.81) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL6386255 | 0.69 | AHR (0.90) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL29263536 | 0.68 | TRPA1 (0.71) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL27892340 | 0.67 | AHR (0.77) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL28089619 | 0.67 | AHR (0.77) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL2945202 | 0.67 | AHR (0.94) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL30877947 | 0.67 | AHR (0.94) | TRPA1CA1CA2ITGB2ICAM1 | |
| Indole SCHEMBL6704453 | 0.67 | AHR (0.41) | TRPA1CA1CA2ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004534033-A | Interleukin-12 8 of the receptor antagonist as new 5-phenyl -1h-1,2,4-triazole-1-ethanol indole derivative | ラボラトワール フルニエ エス・アー | 2004-11-11 | — | — | JP | disclosed |