Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261804 | 0.80 | IMPDH2 (0.45) | IMPDH2GABRA1GABRB2POLB | |
| SCHEMBL10480235 | 0.77 | GABRA1 (0.48) | ALDH1A1MAPTGABRA1GABRB2POLB | |
| SCHEMBL10696450 | 0.77 | ALDH1A1 (0.31) | ALDH1A1MAPTTDP1GABRA1GABRB2 | |
| SCHEMBL11196023 | 0.76 | GABRA1 (0.32) | MAPTGABRA1GABRB2POLBSMN1; SMN2 | |
| SCHEMBL28789107 | 0.73 | GABRA1 (0.38) | MAPTIMPDH2GABRA1GABRB2POLB | |
| SCHEMBL9792845 | 0.73 | CYP3A4 (0.32) | ALDH1A1MAPTTDP1IMPDH2SMN1; SMN2 | |
| SCHEMBL1415804 | 0.72 | IMPDH2 (0.41) | IMPDH2GABRA1GABRB2POLB | |
| SCHEMBL20819282 | 0.72 | CYP3A4 (0.48) | PTGDRPTGDR2ALDH1A1MAPTTDP1 | |
| SCHEMBL10588572 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1918099 | 0.71 | GABRA1 (0.43) | ALDH1A1MAPTIMPDH2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9193667-B2 | Process for the selective meta-chlorination of alkylanilines | LONZA LTD. (CH) | 2015-11-24 | — | — | US | disclosed |
| US-20130338400-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | LONZA LTD. (CH) | 2013-12-19 | — | — | US | disclosed |
| EP-2606028-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | Lonza Ltd (CH) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012022460-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | LONZA LTD (CH) | 2012-02-23 | — | — | WO | disclosed |
| EP-0310732-B1 | PROCESS FOR THE PREPARATION OF N-ACYL-N-ALKYL-2,6-DIALKYL-3-CHLOROANILINES | CIBA-GEIGY AG (CH) | 1992-03-11 | — | — | EP | disclosed |
| EP-0310732-A1 | Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines | CIBA-GEIGY AG (CH) | 1989-04-12 | — | — | EP | disclosed |
| EP-0284555-A1 | Process for the preparation of N-acyl-N-(oxazoliden-2-on-3-yl)-2,6-dialkyl-3-chloroanilines | CIBA-GEIGY AG (CH) | 1988-09-28 | — | — | EP | disclosed |
| US-4721797-A | Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines | CIBA-GEIGY CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4401833-A | Process for the preparation of 4-chloro-2,6-dialkylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338400-A1 | PROCESS FOR THE SELECTIVE META-CHLORINATION OF ALKYLANILINES | CLIC4, CLIC1, NPM1 | PTGDR 4154/4885PTGDR2 4441/4885ALDH1A1 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.