Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378398 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP3A4TSHRMAPK1 | |
| SCHEMBL7729896 | 0.83 | IDO1 (0.44) | ALDH1A1MAPTCYP3A4TSHRMAPK1 | |
| SCHEMBL1538730 | 0.82 | MEN1 (0.45) | ALDH1A1MAPTCYP3A4TSHRL3MBTL1 | |
| SCHEMBL6308371 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTCYP3A4TSHRMAPK1 | |
| SCHEMBL2027813 | 0.78 | MAPT (0.45) | ALDH1A1MAPTCYP3A4TSHRMAPK1 | |
| SCHEMBL4670361 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTCYP3A4CYP1A2TDP1 | |
| SCHEMBL2676531 | 0.77 | NPC1 (0.50) | ALDH1A1MAPTCYP3A4TSHRMAPK1 | |
| SCHEMBL23747623 | 0.76 | NPC1 (0.49) | ALDH1A1MAPTMAPK1KDM4ENPC1 | |
| SCHEMBL2676537 | 0.76 | NPC1 (0.46) | ALDH1A1MAPTMAPK1TDP1KDM4E | |
| SCHEMBL27372 | 0.75 | LMNA (0.42) | ALDH1A1CYP1A2KDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235022-A1 | Quality control method for manufacturing biopolymer arrays | ROCHE DIAGNOSTICS GMBH (DE) | 2004-11-25 | — | — | US | claimed |
| EP-1466663-A1 | Quality control method for manufacturing nucleic acid arrays | F. HOFFMANN-LA ROCHE AG (CH) | 2004-10-13 | — | — | EP | claimed |
| US-20040235022-A1 | Quality control method for manufacturing biopolymer arrays | ROCHE DIAGNOSTICS GMBH (DE) | 2004-11-25 | — | — | US | disclosed |
| EP-1466663-A1 | Quality control method for manufacturing nucleic acid arrays | F. HOFFMANN-LA ROCHE AG (CH) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235022-A1 | Quality control method for manufacturing biopolymer arrays | CTRL, PCBP1, PARG | ALDH1A1 2551/4885MAPT 2010/4885CYP3A4 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.