Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10971610 | 0.82 | PARP1 (0.46) | PARP1ABL1RAD52RIN1ELANE | |
| SCHEMBL8727251 | 0.81 | ELANE (0.39) | PARP1ABL1RAD52RIN1ELANE | |
| SCHEMBL21712343 | 0.81 | ABL1 (0.59) | ACHEABL1RAD52RIN1ELANE | |
| SCHEMBL10444208 | 0.81 | ABL1 (0.37) | PARP1ABL1RAD52RIN1 | |
| SCHEMBL10968723 | 0.79 | ABL1 (0.47) | PARP1ABL1RAD52RIN1ELANE | |
| SCHEMBL5136203 | 0.79 | ABL1 (0.35) | PARP1ABL1RAD52RIN1PIK3CG | |
| SCHEMBL3864343 | 0.78 | ADORA3 (0.41) | BRD4ADORA3ADORA2APIK3CG | |
| SCHEMBL1692289 | 0.78 | TLR7 (0.39) | ABL1RAD52RIN1ELANEADORA2A | |
| SCHEMBL8722636 | 0.78 | DHFR (0.42) | — | |
| SCHEMBL8727256 | 0.77 | TLR8 (0.40) | ABL1RAD52RIN1ELANEADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714608-A | IMMUNOMODULATORS AND ANTIVIRAL AGENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-02-03 | — | — | US | disclosed |