Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827220 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14382185 | 0.77 | KDM4E (0.81) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6705449 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7750980 | 0.73 | KDM4E (0.79) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10528614 | 0.72 | KDM4E (0.64) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9183478 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL8190642 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL29357294 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10645986 | 0.71 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Famciclovir SCHEMBL2949 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891374-A4 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | UNIV COLUMBIA (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0891374-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997027208-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1997-07-31 | — | — | WO | disclosed |