Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoyl Peroxide SCHEMBL7510601 | 0.85 | NR4A2 (0.37) | L3MBTL1KDM4EALDH1A1MCL1BCL2 | |
| SCHEMBL3686690 | 0.84 | — | — | |
| SCHEMBL14992680 | 0.82 | GPR84 (0.39) | L3MBTL1KDM4EALDH1A1GPR84MCL1 | |
| SCHEMBL181183 | 0.76 | HTR2A (0.41) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL2880031 | 0.73 | PKM (0.40) | L3MBTL1KDM4EMEN1KMT2AHTR2A | |
| SCHEMBL2009535 | 0.73 | KDM4E (0.33) | L3MBTL1KDM4EKMT2A | |
| SCHEMBL2880278 | 0.73 | CYP1A2 (0.34) | MEN1KMT2A | |
| SCHEMBL16871893 | 0.73 | SLC5A2 (0.37) | — | |
| SCHEMBL474102 | 0.72 | HTR2A (0.46) | ALDH1A1MEN1KMT2AHTR2ASLC6A4 | |
| SCHEMBL661988 | 0.72 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1GPR84GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058988-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2004-03-25 | — | — | US | disclosed |
| US-20030220392-A1 | Fatty acid synthase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-27 | — | — | US | disclosed |
| EP-1299376-A1 | FATTY ACID SYNTHASE INHIBITORS | Smithkline Beecham (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6498187-B1 | SUCH AS 2'-(6-CHLOROPIPERONYL)-3-(2,6-DICHLOROBENZYLOXY)-CINNAMIC ACID; ANTIBIOTICS | SMITHKLINE BEECHAM CORPORATION | 2002-12-24 | — | — | US | disclosed |
| WO-2001090099-A1 | FATTY ACID SYNTHASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220392-A1 | Fatty acid synthase inhibitors | FASN, FADS1, FADS2 | L3MBTL1 3206/4885KDM4E 2316/4885ALDH1A1 985/4885 |
| US-20040058988-A1 | FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | L3MBTL1 3206/4885KDM4E 2316/4885ALDH1A1 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.