Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.51 |
| ▸ | CASP1 | P29466 | 11/20 | 0.51 |
| ▸ | CASP7 | P55210 | 11/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.51 |
| ▸ | HPGD | P15428 | 9/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.45 |
| ▸ | USP2 | O75604 | 5/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920903 | 0.86 | CHRNB2 (0.46) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL2921304 | 0.85 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL3368105 | 0.83 | CHRNB2 (0.52) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL3366838 | 0.83 | CHRNB2 (0.52) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL2921147 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL1132491 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL31398803 | 0.76 | CHRNB2 (0.56) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL29478525 | 0.74 | MAPT (0.47) | ALDH1A1CASP1KDM4EMAPTUSP2 | |
| SCHEMBL6705489 | 0.72 | KDM1A (0.76) | ALDH1A1CYP1A2CYP3A4USP2PDGFRB | |
| SCHEMBL29922379 | 0.71 | KIT (0.41) | PDGFRBKITPDGFRAPDPK1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259881-A1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO, LTD. (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1309567-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | Millennium Pharmaceuticals, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002016360-A2 | NITROGENOUS HETEROCYCLIC COMPOUNDS | COR THERAPEUTICS, INC. (US) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259881-A1 | Nitrogenous heterocyclic compounds | WNK2, CDK5, PDGFRA | ALDH1A1 3597/4885CYP1A2 4602/4885CASP1 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.