Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559356 | 0.84 | SLC16A3 (0.60) | KCNQ2MAPTKCNQ3CYP1A2CYP3A4 | |
| SCHEMBL6707495 | 0.80 | CRHBP (0.71) | KCNQ2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28513100 | 0.78 | MAPK1 (0.49) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6340417 | 0.76 | CYSLTR2 (0.49) | MAPTCRHBPCRHR2L3MBTL1NPSR1 | |
| SCHEMBL2970624 | 0.76 | FFAR1 (0.48) | — | |
| SCHEMBL15697660 | 0.75 | L3MBTL1 (0.65) | MAPTCYP2D6CYP2C9ALDH1A1MEN1 | |
| SCHEMBL3456848 | 0.75 | KCNQ2 (0.64) | KCNQ2MAPTKCNQ3CYP1A2CYP3A4 | |
| SCHEMBL11266416 | 0.74 | HDAC3 (0.52) | MAPTCYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL13166879 | 0.73 | KCNQ2 (0.66) | KCNQ2MAPTKCNQ3CYP1A2CYP3A4 | |
| SCHEMBL7752354 | 0.73 | ALDH1A1 (0.82) | KCNQ2MAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040068013-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. | 2004-04-08 | — | — | US | disclosed |
| US-6663887-B2 | Modified amino acid compounds | EMISPHERE TECHNOLOGIES, INC. | 2003-12-16 | — | — | US | disclosed |
| EP-0783299-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2003-09-10 | — | — | EP | disclosed |
| US-20020120009-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. | 2002-08-29 | — | — | US | disclosed |
| US-20010003001-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. | 2001-06-07 | — | — | US | disclosed |
| US-6100298-A | MIXTURE OF DRUG AND N-(4-(CARBOXYPROPYL)PHENYL-4-PHENYL-BUTYRAMIDE FOR IMPROVED ORAL DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-08-08 | — | — | US | disclosed |
| US-5955503-A | MODIFIED AMINO ACID COMPOUNDS USEFUL AS CARRIERS IN THE DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SUCH AS, FOR EXAMPLE, BIOACTIVE PEPTIDES AND THE LIKE | EMISPHERE TECHNOLOGIES, INC. (US) | 1999-09-21 | — | — | US | disclosed |
| US-5643957-A | MODIFIED AMINO ACIDS, SIMPLE, INEXPENSIVE | EMISPHERE TECHNOLOGIES, INC. (US) | 1997-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068013-A1 | Compounds and compositions for delivering active agents | DNPEP, SLC7A1, SERPINB1 | KCNQ2 4806/4885MAPT 1501/4885KCNQ3 4792/4885 |
| US-20020120009-A1 | Compounds and compositions for delivering active agents | DNPEP, SLC7A1, SERPINB1 | KCNQ2 4806/4885MAPT 1501/4885KCNQ3 4792/4885 |
| US-20010003001-A1 | Compounds and compositions for delivering active agents | DNPEP, SLC7A1, SERPINB1 | KCNQ2 4806/4885MAPT 1501/4885KCNQ3 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.