SCHEMBL6706197

SCHEMBL6706197

O=C(CCC(=O)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
HIF1A Q16665 1/20 0.42
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
VCAM1 P19320 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2991701 0.91 LMNA (0.39) CYP1A2CYP2C9HIF1AALDH1A1LMNA
SCHEMBL2885765 0.86 ALDH1A1 (0.46) CYP1A2CYP2C9HIF1AALDH1A1LMNA
SCHEMBL11233782 0.84 CYP1A2 (0.42) CYP1A2CYP2C9HIF1ACA1CA2
SCHEMBL2886933 0.83 TSHR (0.47) CYP1A2CYP2C9HIF1AALDH1A1LMNA
SCHEMBL2597460 0.82 CYP1A2 (0.41) CYP1A2CYP2C9HIF1ATSHRCA1
SCHEMBL2885833 0.80 HIF1A (0.44) CYP1A2CYP2C9HIF1AALDH1A1LMNA
SCHEMBL3456634 0.80 DGKA (0.50) ALDH1A1LMNAMAPTKMT2ATSHR
SCHEMBL1507483 0.80 DGKA (0.50) ALDH1A1LMNAMAPTKMT2ATSHR
SCHEMBL414238 0.80 DGKA (0.50) ALDH1A1LMNAMAPTKMT2ATSHR
SCHEMBL3504478 0.78 CYP1A2 (0.34) CYP1A2CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040215010-A1 Universal solid supports for solid phase oligosynthesis and methods for their preparation and use PROLIGO, LLC 2004-10-28 US disclosed
EP-1289911-A2 UNIVERSAL SOLID SUPPORTS FOR SOLID PHASE OLIGOSYNTHESIS AND METHODS FOR THEIR PREPARATION AND USE Proligo LLC (US) 2003-03-12 EP disclosed
WO-2001096357-A2 UNIVERSAL SOLID SUPPORTS FOR SOLID PHASE OLIGOSYNTHESIS AND METHODS FOR THEIR PREPARATION AND USE PROLIGO LLC (US) 2001-12-20 WO disclosed
WO-1990003381-A1 METHOD OF SYNTHESIS OF ALPHA OLIGORIBONUCLEOTIDES AND COMPOUNDS USEFUL FOR THE METHOD CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1990-04-05 WO disclosed
EP-0360626-A1 Process for the synthesis of alpha-oligoribonucleotides, and components useful in the process CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1990-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040215010-A1 Universal solid supports for solid phase oligosynthesis and methods for their preparation and use POLRMT, POLR2H, POLL CYP1A2 4347/4885CYP2C9 2918/4885HIF1A 2884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.