Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 11/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708680 | 0.88 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL7029929 | 0.68 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL6706575 | 0.64 | KDM4E (0.39) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL15387442 | 0.64 | KDM4E (0.66) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL30287119 | 0.63 | MAPT (0.64) | ALDH1A1LMNAMAPTCYP1A2CYP2C9 | |
| SCHEMBL26087969 | 0.63 | MAPT (0.64) | ALDH1A1LMNAMAPTCYP1A2CYP2C9 | |
| SCHEMBL6708754 | 0.62 | KDM4E (0.80) | ALDH1A1LMNAMAPTKDM4EHPGD | |
| SCHEMBL13778134 | 0.60 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTKDM4ECYP2D6 | |
| SCHEMBL6220871 | 0.59 | MAPT (0.35) | ALDH1A1MAPTKDM4ECYP2D6CYP2C19 | |
| SCHEMBL2314317 | 0.59 | SMN1; SMN2 (0.56) | ALDH1A1LMNAMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | NATCO PHARMA LIMITED (IN) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | CBR1, CYP4X1, NRAS | ALDH1A1 1601/4885LMNA 3085/4885MAPT 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.