Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 9/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCND2 | P30279 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504558 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1CDK4CCND1CCND2 | |
| Hydrochloric Acid SCHEMBL25379174 | 0.69 | ALDH1A1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL25377498 | 0.69 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL63698 | 0.68 | MAPT (0.63) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21858310 | 0.66 | KDM4E (0.53) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3774230 | 0.65 | HSD11B1 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL9593010 | 0.65 | MAT2A (0.45) | ALDH1A1MEN1KMT2AENPP2MAPK8 | |
| SCHEMBL7101103 | 0.65 | KDM4E (0.80) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8320029 | 0.64 | ALK (0.55) | KDM4EALDH1A1ALKMAPTGFER | |
| SCHEMBL24590421 | 0.62 | ALK (0.62) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | NATCO PHARMA LIMITED (IN) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073030-A1 | Process for the preparation of quinolone derivatives | CBR1, CYP4X1, NRAS | KDM4E 3682/4885ALDH1A1 1601/4885ALK 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.