Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057057 | 0.84 | CYP3A4 (0.59) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 | |
| SCHEMBL6707593 | 0.82 | CYP19A1 (0.36) | CYP3A4CYP19A1KMT2AOGG1PTGS2 | |
| SCHEMBL11119666 | 0.79 | CYP3A4 (0.52) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 | |
| SCHEMBL9308406 | 0.78 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 | |
| SCHEMBL9302133 | 0.78 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 | |
| SCHEMBL10713754 | 0.78 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 | |
| SCHEMBL10813992 | 0.78 | OGG1 (0.54) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 | |
| SCHEMBL10434458 | 0.77 | CYP3A4 (0.50) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 | |
| SCHEMBL10810883 | 0.76 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 | |
| SCHEMBL10655518 | 0.76 | CYP3A4 (0.50) | CYP3A4CYP2C9CYP2C19HSP90AA1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | YANG JI CHEMICAL COMPANY LTD (KR) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | IDO1, IDO2, TPH1 | CYP3A4 158/4885CYP2C9 702/4885CYP2C19 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.