Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711720 | 0.91 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9AHTTKMT2A | |
| SCHEMBL6710449 | 0.90 | KMT2A (0.43) | SMN1; SMN2NPC1RAB9AHTTKMT2A | |
| SCHEMBL6712158 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AHTTKMT2A | |
| SCHEMBL6711696 | 0.87 | GRIK1 (0.39) | POLBLMNAGRIK1 | |
| SCHEMBL6708757 | 0.82 | GRIK1 (0.42) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6708679 | 0.82 | GRIK1 (0.44) | POLBGRIK1 | |
| SCHEMBL6713707 | 0.81 | MEN1 (0.38) | SMN1; SMN2NPC1RAB9AHTTKMT2A | |
| SCHEMBL6713760 | 0.81 | GRIK1 (0.42) | KMT2AMEN1GRIK1 | |
| SCHEMBL6713262 | 0.80 | GRIK1 (0.41) | SMN1; SMN2KMT2AMEN1POLBLMNA | |
| SCHEMBL6710166 | 0.80 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ALMNAGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | SMN1; SMN2 2635/4885NPC1 3891/4885RAB9A 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.