Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713760 | 0.96 | GRIK1 (0.42) | GRIK1TDP1GPR35NSD2RXFP1 | |
| SCHEMBL6713931 | 0.94 | GRIK1 (0.41) | GRIK1TDP1GPR35NSD2RXFP1 | |
| SCHEMBL6709929 | 0.93 | GRIK1 (0.49) | GRIK1TDP1GPR35MAPT | |
| SCHEMBL6708757 | 0.93 | GRIK1 (0.42) | GRIK1TDP1GPR35NSD2RXFP1 | |
| SCHEMBL6712044 | 0.92 | GPR35 (0.46) | GRIK1GPR35RXFP1MAPTTP53 | |
| SCHEMBL6710166 | 0.92 | NPC1 (0.43) | GRIK1 | |
| SCHEMBL6713714 | 0.91 | KDR (0.43) | GRIK1TDP1GPR35MAPTTP53 | |
| SCHEMBL6711406 | 0.90 | GRIK1 (0.38) | GRIK1TDP1GPR35NSD2RXFP1 | |
| SCHEMBL6713262 | 0.90 | GRIK1 (0.41) | GRIK1TDP1GPR35NSD2MAPT | |
| SCHEMBL6713519 | 0.90 | GRIK1 (0.41) | GRIK1TDP1GPR35NSD2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885TDP1 2977/4885GPR35 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.