Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712041 | 0.94 | LMNA (0.41) | PARP14POLBKCNQ2PLCG2ROCK2 | |
| SCHEMBL6708944 | 0.93 | PARP14 (0.39) | PARP14POLBRXFP1MAPTTP53 | |
| SCHEMBL6708820 | 0.92 | PARP14 (0.41) | PARP14POLBTP53PLCG2LMNA | |
| SCHEMBL6707755 | 0.91 | PARP14 (0.43) | PARP14POLBTP53PLCG2HDAC2 | |
| SCHEMBL6709118 | 0.91 | PTK2B (0.40) | PARP14POLBTP53KCNQ2PLCG2 | |
| SCHEMBL6708738 | 0.91 | PARP14 (0.43) | PARP14POLBRXFP1MAPTTP53 | |
| SCHEMBL6713088 | 0.90 | PARP14 (0.45) | PARP14RXFP1MAPTTP53KCNQ2 | |
| SCHEMBL6714087 | 0.90 | NPY5R (0.42) | PARP14POLBPLCG2HDAC3HDAC1 | |
| SCHEMBL6714191 | 0.90 | PARP14 (0.45) | PARP14POLBMAPTTP53KCNQ2 | |
| SCHEMBL6713933 | 0.89 | RXFP1 (0.41) | POLBRXFP1MAPTTP53KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PARP14 2597/4885POLB 626/4885RXFP1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.