Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713703 | 0.91 | AKR1C2 (0.40) | PLA2G4AMAPTLMNAGRIK1PLA2G2A | |
| SCHEMBL6711779 | 0.89 | RXFP1 (0.43) | RXFP1MAPTLMNAKDM1AGRM4 | |
| SCHEMBL6714061 | 0.89 | PLA2G4A (0.39) | PLA2G4AMAPTLMNAKDM1APLA2G2A | |
| SCHEMBL6709188 | 0.88 | SRD5A2 (0.42) | RXFP1MAPTKDM1AGRM4GRIK1 | |
| SCHEMBL6708946 | 0.88 | KDM1A (0.41) | RXFP1KDM1AGRM4GRIK1ROCK1 | |
| SCHEMBL6707925 | 0.88 | RXFP1 (0.39) | RXFP1MAPTLMNAKDM1AGRM4 | |
| SCHEMBL6708850 | 0.87 | KDM1A (0.41) | RXFP1KDM1AGRM4GRIK1ROCK1 | |
| SCHEMBL6712110 | 0.85 | EPHX1 (0.42) | RXFP1GRM4GRIK1PLA2G2A | |
| SCHEMBL6711593 | 0.85 | RXFP1 (0.43) | RXFP1LMNAGRM4GRIK1ROCK1 | |
| SCHEMBL6709851 | 0.84 | RXFP1 (0.39) | RXFP1MAPTLMNAKDM1AGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | RXFP1 3836/4885PLA2G4A 4558/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.