SCHEMBL6712110

SCHEMBL6712110

CCCCCNC(=O)Nc1ccc2cc(C(=O)Nc3ccc(Cl)cc3-c3noc(=O)[nH]3)n(C)c2c1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 5/20 0.42
GRIK1 P39086 1/20 0.42
RXFP1 Q9HBX9 1/20 0.40
EPHX2 P34913 6/20 0.40
PLA2G2A P14555 2/20 0.38
ALOX15 P16050 1/20 0.38
GRM4 Q14833 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6710606 0.92 GRIK1 (0.40) EPHX1GRIK1RXFP1EPHX2PLA2G2A
SCHEMBL6710344 0.90 EPHX1 (0.38) EPHX1RXFP1EPHX2PLA2G2A
SCHEMBL6711593 0.88 RXFP1 (0.43) GRIK1RXFP1GRM4
SCHEMBL6713555 0.86 RXFP1 (0.46) GRIK1RXFP1GRM4
SCHEMBL6711896 0.85 EPHX1 (0.43) EPHX1RXFP1EPHX2ALOX15GRM4
SCHEMBL6707744 0.85 RXFP1 (0.40) GRIK1RXFP1PLA2G2AGRM4
SCHEMBL6713186 0.84 RXFP1 (0.42) GRIK1RXFP1GRM4
SCHEMBL6709891 0.83 RXFP1 (0.46) GRIK1RXFP1GRM4
SCHEMBL6711479 0.82 RXFP1 (0.41) GRIK1RXFP1GRM4
SCHEMBL6710208 0.82 RXFP1 (0.44) GRIK1RXFP1ALOX15GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040142981-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142981-A1 Antibacterial benzoic acid derivatives GABRD, PHB1, GABBR1 EPHX1 1869/4885GRIK1 3885/4885RXFP1 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.