Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708936 | 0.92 | KDM1A (0.34) | LMNAMAPTRXFP1BRD4SMN1; SMN2 | |
| SCHEMBL6710432 | 0.90 | LMNA (0.35) | LMNAMAPTRXFP1BRD4SMN1; SMN2 | |
| SCHEMBL6709981 | 0.90 | LMNA (0.35) | LMNAMAPTRXFP1BRD4SMN1; SMN2 | |
| SCHEMBL6710193 | 0.89 | PPARG (0.36) | LMNAMAPTRXFP1SMN1; SMN2 | |
| SCHEMBL6710109 | 0.89 | NPSR1 (0.35) | LMNAMAPTRXFP1HSD17B10 | |
| SCHEMBL6713474 | 0.88 | RXFP1 (0.33) | LMNAMAPTRXFP1SMN1; SMN2HSD17B10 | |
| SCHEMBL6710365 | 0.87 | KDM1A (0.39) | LMNAMAPTRXFP1BRD4KDM1A | |
| SCHEMBL6709131 | 0.87 | PPIA (0.39) | LMNAMAPTRXFP1KDM1A | |
| SCHEMBL6711750 | 0.86 | KDM1A (0.39) | LMNAMAPTRXFP1KDM1A | |
| SCHEMBL6710191 | 0.86 | ALK (0.38) | LMNAMAPTRXFP1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | LMNA 4062/4885MAPT 4754/4885RXFP1 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.