SCHEMBL6708936

SCHEMBL6708936

COCCOc1cccc2cc(C(=O)Nc3ccc(C#N)cc3-c3nnn[nH]3)n(C)c12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
MAOA P21397 1/20 0.33
PDGFRB P09619 2/20 0.33
BRD4 O60885 1/20 0.33
BRPF1 P55201 1/20 0.33
MMP3 P08254 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ADORA2A P29274 2/20 0.32
ALB P02768 1/20 0.32
MCHR1 Q99705 1/20 0.32
FBP1 P09467 1/20 0.32
GPR6 P46095 1/20 0.32
CSF1R P07333 1/20 0.32
KIT P10721 1/20 0.32
FASN P49327 1/20 0.32
LCK P06239 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6709981 0.92 LMNA (0.35) LMNAMAPTRXFP1BRD4SMN1; SMN2
SCHEMBL6710432 0.92 LMNA (0.35) KDM1ALMNAMAPTRXFP1MAOA
SCHEMBL6707789 0.92 LMNA (0.33) KDM1ALMNAMAPTRXFP1BRD4
SCHEMBL6711764 0.90 GCK (0.33) KDM1ALMNAMAPTADORA2AFBP1
SCHEMBL6710365 0.89 KDM1A (0.39) KDM1ALMNAMAPTRXFP1MAOA
SCHEMBL6709131 0.89 PPIA (0.39) KDM1ALMNAMAPTRXFP1
SCHEMBL6713474 0.88 RXFP1 (0.33) KDM1ALMNAMAPTRXFP1SMN1; SMN2
SCHEMBL6712280 0.88 NPSR1 (0.36) LMNAMAPTRXFP1BRPF1HSD17B10
SCHEMBL6707977 0.88 IRAK4 (0.37) LMNAMAPTRXFP1BRPF1LCK
SCHEMBL6711750 0.88 KDM1A (0.39) KDM1ALMNAMAPTRXFP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040142981-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142981-A1 Antibacterial benzoic acid derivatives GABRD, PHB1, GABBR1 KDM1A 620/4885LMNA 4062/4885MAPT 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.