Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709095 | 0.93 | GRIK1 (0.37) | PARP14ALDH1A1GRIK1NHERF1 | |
| SCHEMBL6710251 | 0.93 | PARP14 (0.35) | PARP14PLA2G7GRIK1EPAS1 | |
| SCHEMBL6710182 | 0.92 | ALDH1A1 (0.40) | PARP14ALDH1A1PLA2G7MAPK8MAPK9 | |
| SCHEMBL6708561 | 0.91 | NSD2 (0.39) | PARP14ALDH1A1PLA2G7MAPK8MAPK9 | |
| SCHEMBL6710278 | 0.90 | PARP14 (0.43) | PARP14ALDH1A1PLA2G7GRIK1NHERF1 | |
| SCHEMBL6709308 | 0.90 | TP53 (0.41) | ALDH1A1PLA2G7MAPK8MAPK9HDAC1 | |
| SCHEMBL6709207 | 0.89 | PARP14 (0.43) | PARP14ALDH1A1PLA2G7HDAC1IDO1 | |
| SCHEMBL6711745 | 0.89 | PLA2G7 (0.38) | PARP14ALDH1A1PLA2G7BRD4HDAC1 | |
| SCHEMBL6714135 | 0.89 | PARP14 (0.41) | PARP14GRIK1KCNQ2 | |
| SCHEMBL6707895 | 0.89 | PARP14 (0.39) | PARP14ALDH1A1PLA2G7GRIK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | PARP14 2597/4885ALDH1A1 123/4885VNN1 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.