Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28807848 | 0.78 | ENPP2 (0.57) | ENPP2KMT2AMMP3NPC1PTPRC | |
| SCHEMBL11532120 | 0.76 | L3MBTL1 (0.49) | KMT2APKML3MBTL1GAAFLT3 | |
| SCHEMBL28229775 | 0.76 | SYK (0.37) | L3MBTL1GAAMMP3MAPTKDM4E | |
| SCHEMBL3800806 | 0.75 | CA1 (0.38) | ENPP2KMT2A | |
| SCHEMBL2154504 | 0.75 | KMT2A (0.47) | ENPP2KMT2APKML3MBTL1GAA | |
| SCHEMBL1251529 | 0.74 | LTA4H (0.50) | ENPP2KMT2AMMP3 | |
| SCHEMBL3591237 | 0.72 | ST14 (0.50) | MAOB | |
| SCHEMBL2202099 | 0.72 | ENPP2 (0.52) | ENPP2KMT2APKMMMP3RAB9A | |
| SCHEMBL17215124 | 0.72 | GAA (0.43) | KMT2APKML3MBTL1GAAMMP3 | |
| SCHEMBL13203140 | 0.72 | PKM (0.41) | ENPP2KMT2APKML3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412973-A | Nitrogen-containing fused heteroaromatic bicyclic compounds as USP1 inhibitors and uses thereof | 上海瑛派药业有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-102917590-A | Trycyclic compounds and pbk inhibitors containing the same | ONCOTHERAPY SCIENCE INC | 2013-02-06 | — | — | CN | disclosed |
| CN-1277823-C | New benzothiazine and benzothiadiazine compounds,its preparation process and pharmaceutical composition containing said compounds | SERVIER LAB (FR) | 2006-10-04 | — | — | CN | disclosed |
| CN-1572791-A | New benzothiazine and benzothiadiazine compounds,its preparation process and pharmaceutical composition containing said compounds | SERVIER LAB (FR) | 2005-02-02 | — | — | CN | disclosed |
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | ENPP2 487/4885KMT2A 406/4885PKM 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.