Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708201 | 0.84 | GRIN2B (0.48) | KDM4EALDH1A1MCHR1HRH3CYP2D6 | |
| SCHEMBL6704583 | 0.84 | MCHR1 (0.45) | ACHEHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL6708212 | 0.84 | L3MBTL1 (0.41) | ACHEHDAC1HDAC8HDAC6KDM4E | |
| Hydrochloric Acid SCHEMBL6705586 | 0.83 | MCHR1 (0.44) | ACHEHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL6223200 | 0.79 | HRH3 (0.61) | HDAC1HDAC8HDAC6KDM4EALDH1A1 | |
| SCHEMBL6708035 | 0.78 | GRIN2B (0.42) | ACHEKDM4EALDH1A1MCHR1BCHE | |
| SCHEMBL28610633 | 0.77 | PRMT6 (0.63) | KDM4EGAAALDH1A1HRH3SMN1; SMN2 | |
| SCHEMBL6708235 | 0.77 | ALDH1A1 (0.50) | ACHEKDM4EALDH1A1BCHEHRH3 | |
| SCHEMBL6224393 | 0.76 | HRH3 (0.55) | HDAC1HDAC8HDAC6KDM4EGAA | |
| SCHEMBL28126426 | 0.76 | CA2 (0.47) | KDM4EGAAALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242572-A1 | New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture | MCHR2, MCHR1, NPY1R | ACHE 3666/4885HDAC1 2047/4885HDAC8 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.