Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.61 |
| ▸ | CTSL | P07711 | 8/20 | 0.61 |
| ▸ | CTSK | P43235 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686218 | 0.78 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL6690844 | 0.77 | CTSS (0.62) | CTSSCTSLCTSKLMNATHRB | |
| SCHEMBL4798799 | 0.77 | CTSS (0.70) | CTSSCTSLCTSK | |
| SCHEMBL4798807 | 0.77 | CTSS (0.70) | CTSSCTSLCTSK | |
| SCHEMBL6690317 | 0.77 | CTSS (0.70) | CTSSCTSLCTSKLMNAHSD17B10 | |
| SCHEMBL4799054 | 0.76 | CTSS (0.76) | CTSSCTSLCTSK | |
| SCHEMBL4799060 | 0.76 | CTSS (0.76) | CTSSCTSLCTSK | |
| SCHEMBL4797798 | 0.76 | CTSL (1.00) | CTSSCTSLCTSK | |
| SCHEMBL4797808 | 0.76 | CTSL (1.00) | CTSSCTSLCTSK | |
| SCHEMBL4803510 | 0.75 | CTSS (0.85) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248887-A1 | Inhibitors of cathepsin S | IRM LLC (BM) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248887-A1 | Inhibitors of cathepsin S | CTSS, CTSB, CTSZ | CTSS 1/4885CTSL 11/4885CTSK 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.