Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15562633 | 0.88 | ALDH1A1 (0.49) | CYP3A4HTR3AALDH1A1ATMMAPT | |
| SCHEMBL2793777 | 0.85 | CYP3A4 (0.50) | CYP3A4HTR3AALDH1A1MAPTMEN1 | |
| SCHEMBL13229697 | 0.83 | CYP3A4 (0.49) | CYP3A4HTR3AALDH1A1MAPTMEN1 | |
| SCHEMBL13229581 | 0.80 | CYP3A4 (0.55) | CYP3A4HTR3AALDH1A1MAPTKMT2A | |
| SCHEMBL10472393 | 0.77 | GABRA1 (0.52) | CYP3A4HTR3AHTR2AHTR2CHTR2B | |
| SCHEMBL31549260 | 0.75 | F7 (0.43) | CYP3A4HTR3AALDH1A1MAPTMEN1 | |
| SCHEMBL13229587 | 0.75 | CFTR (0.63) | CYP3A4HTR3AALDH1A1MEN1KMT2A | |
| SCHEMBL6332699 | 0.73 | ALDH1A1 (0.42) | ALDH1A1ATMMAPTMEN1KMT2A | |
| SCHEMBL6479523 | 0.72 | POLB (0.56) | CYP3A4HTR3AKMT2ANPC1RAB9A | |
| SCHEMBL13229624 | 0.71 | CFTR (0.48) | CYP3A4HTR3AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248927-A1 | Preventive agent/remedial agent for constipation predominant ibs | MITSUBISHI PHARMA CORPORATION (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-0269295-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248927-A1 | Preventive agent/remedial agent for constipation predominant ibs | BRS3, SLC10A2, FABP2 | CYP3A4 2819/4885HTR3A 25/4885ALDH1A1 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.