Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.38 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.38 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710116 | 0.94 | GPR27 (0.40) | ALDH1A1GPR27AVPR2HIF1AGRIK1 | |
| SCHEMBL6713213 | 0.92 | MEN1 (0.39) | ALDH1A1GPR27AVPR2GRIK1SLC10A2 | |
| SCHEMBL6714102 | 0.92 | GPR27 (0.42) | GPR27AVPR2HIF1AGRIK1SLC10A2 | |
| SCHEMBL6710483 | 0.91 | HIF1A (0.46) | ALDH1A1GPR27AVPR2HIF1AGRIK1 | |
| SCHEMBL6709874 | 0.88 | GRIK1 (0.39) | HIF1AGRIK1MAPTMEN1KMT2A | |
| SCHEMBL6709830 | 0.88 | BRD4 (0.39) | HIF1AGRIK1BRD4ROCK1 | |
| SCHEMBL6707931 | 0.88 | GPR27 (0.41) | ALDH1A1GPR27AVPR2HIF1AMEN1 | |
| SCHEMBL6914244 | 0.88 | MEN1 (0.36) | ALDH1A1GPR27GRIK1SLC10A2SLC10A1 | |
| SCHEMBL6708097 | 0.87 | HIF1A (0.43) | ALDH1A1HIF1AGRIK1MAPTNPSR1 | |
| SCHEMBL6708030 | 0.86 | ALDH1A1 (0.39) | ALDH1A1GPR27AVPR2HIF1ASLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ALDH1A1 123/4885GPR27 1616/4885AVPR2 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.