Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.41 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710141 | 0.93 | GRIK1 (0.44) | GRIK1PLCG2STK33PLA2G7NHERF1 | |
| SCHEMBL6708679 | 0.93 | GRIK1 (0.44) | GRIK1GPR35TDP1MAPT | |
| SCHEMBL6713155 | 0.90 | SERPINE1 (0.48) | GRIK1PLCG2STK33MAPTNHERF1 | |
| SCHEMBL6709173 | 0.89 | GRIK1 (0.44) | GRIK1PLCG2STK33TDP1MAPT | |
| SCHEMBL6713760 | 0.89 | GRIK1 (0.42) | GRIK1STK33GPR35TDP1MAPT | |
| SCHEMBL6713656 | 0.89 | GRIK1 (0.42) | GRIK1PLCG2STK33MAPTPLA2G7 | |
| SCHEMBL6709991 | 0.89 | KDR (0.44) | GRIK1PLCG2STK33MAPTPLA2G7 | |
| SCHEMBL6708655 | 0.89 | NHERF1 (0.46) | GRIK1PLCG2STK33NHERF1GAA | |
| SCHEMBL6707691 | 0.88 | GRIK1 (0.41) | GRIK1PLCG2STK33TDP1MAPT | |
| SCHEMBL6713714 | 0.88 | KDR (0.43) | GRIK1STK33GPR35TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885PLCG2 4289/4885STK33 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.