Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.33 |
| ▸ | F11 | P03951 | 2/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708711 | 1.00 | IRAK4 (0.38) | IRAK4GRIK1F2F10RXFP1 | |
| SCHEMBL6918564 | 0.93 | KDM1A (0.34) | IRAK4GRIK1CMKLR1F11KLKB1 | |
| SCHEMBL6708862 | 0.92 | GRIK1 (0.36) | GRIK1RXFP1ABL1CMKLR1F11 | |
| SCHEMBL6710035 | 0.91 | GRIK1 (0.36) | IRAK4GRIK1ABL1GRM5ROCK1 | |
| SCHEMBL6710032 | 0.91 | GRIK1 (0.36) | IRAK4GRIK1ABL1GRM5ROCK1 | |
| SCHEMBL6707657 | 0.89 | ALK (0.40) | RXFP1ABL1PPARGLMNAMAPT | |
| SCHEMBL6707654 | 0.89 | ALK (0.40) | RXFP1ABL1PPARGLMNAMAPT | |
| SCHEMBL6711990 | 0.88 | GRIK1 (0.40) | IRAK4GRIK1F10RXFP1F11 | |
| SCHEMBL6709189 | 0.87 | GRIK1 (0.39) | GRIK1RXFP1CMKLR1GRM4GRM5 | |
| SCHEMBL6713393 | 0.87 | GRIK1 (0.39) | GRIK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | IRAK4 1592/4885GRIK1 3885/4885F2 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.