Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711990 | 0.93 | GRIK1 (0.40) | GRIK1LMNAMAPTGRM5RXFP1 | |
| SCHEMBL6710184 | 0.92 | GRIK1 (0.38) | GRIK1CMKLR1LMNAMAPTGRM5 | |
| SCHEMBL6708695 | 0.91 | GRIK1 (0.38) | GRIK1TP53CMKLR1LMNAMAPT | |
| SCHEMBL6712425 | 0.91 | TP53 (0.38) | GRIK1TP53TSHRLMNAMAPT | |
| SCHEMBL6710160 | 0.89 | TP53 (0.36) | TP53TSHRLMNAMAPTRXFP1 | |
| SCHEMBL6713393 | 0.89 | GRIK1 (0.39) | GRIK1TSHRMAPTPTGER1 | |
| SCHEMBL6710303 | 0.88 | ALDH1A1 (0.38) | GRIK1TP53TSHRLMNAMAPT | |
| SCHEMBL6713869 | 0.88 | GRIK1 (0.38) | GRIK1CMKLR1PTGER1 | |
| SCHEMBL6708708 | 0.87 | IRAK4 (0.38) | GRIK1CMKLR1LMNAMAPTGRM5 | |
| SCHEMBL6708711 | 0.87 | IRAK4 (0.38) | GRIK1CMKLR1LMNAMAPTGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885TP53 2699/4885TSHR 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.