Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558121 | 0.81 | TAAR1 (0.55) | TAAR1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL3778213 | 0.78 | PTGES2 (0.54) | TAAR1ALDH1A1KDM4EERN1PTGES2 | |
| SCHEMBL3778217 | 0.78 | PTGES2 (0.54) | TAAR1ALDH1A1KDM4EERN1PTGES2 | |
| SCHEMBL394300 | 0.76 | TAAR1 (0.76) | TAAR1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL30487922 | 0.73 | TAAR1 (0.73) | TAAR1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL1310216 | 0.73 | ALDH1A1 (0.75) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL1310214 | 0.73 | ALDH1A1 (0.75) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL334479 | 0.72 | ALDH1A1 (0.74) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL6016496 | 0.72 | ALDH1A1 (0.74) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL6878713 | 0.72 | LMNA (0.51) | ALDH1A1TRPA1LMNAALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174974-A | Pyrano [3,2-b ] benzofuran-2-one framework compound and synthetic method and application thereof | 新乡学院 | 2021-01-05 | — | — | CN | disclosed |
| EP-1109551-A4 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | COMPETITIVE TECH INC (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1109551-A1 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | Competitive Technologies, Inc. (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000010564-A1 | 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES | COMPETITIVE TECHNOLOGIES, INC. (US) | 2000-03-02 | — | — | WO | disclosed |