Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 3/20 | 0.44 |
| ▸ | CCND1 | P24385 | 3/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016496 | 1.00 | ALDH1A1 (0.74) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Biphenyl SCHEMBL4693704 | 0.93 | ALDH1A1 (0.86) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL14262692 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL28599267 | 0.86 | ALDH1A1 (0.90) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL25267814 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL3442 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL2203965 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Cinnamic Aldehyde SCHEMBL1866630 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Cinnamic Aldehyde SCHEMBL159856 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL28377500 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TRPA1LMNAALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388435-A | 4-Vinyl dihydrofuran-3, 3 (2H) -disulfonyl difluoro compound, and preparation and application thereof | 上海大学 | 2024-07-26 | — | — | CN | disclosed |
| EP-3546454-B1 | BENZOHETEROCYCLYL ALKYLAMINE COMPOUND AND USE THEREOF | UNIV EAST CHINA SCIENCE & TECH (CN) | 2023-09-27 | — | — | EP | disclosed |
| CN-114105993-B | Synthesis method of chiral pyrroloimidazole compound | 大连理工大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-108101826-B | Indole-substituted alkylamine compound and application thereof | 华东理工大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-114105993-A | Synthesis method of chiral pyrroloimidazole compound | 大连理工大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-108117534-B | Benzo-oxygenated aliphatic cyclomethylamines | 华东理工大学 | 2021-02-05 | — | — | CN | disclosed |
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| CN-108084125-B | Benzoheterocyclylalkylamines and their use | 华东理工大学 | 2020-08-18 | — | — | CN | disclosed |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-10-17 | — | — | US | disclosed |
| EP-3546454-A1 | BENZOHETEROCYCLYL ALKYLAMINE COMPOUND AND USE THEREOF | East China University of Science and Technology (CN) | 2019-10-02 | — | — | EP | disclosed |
| US-20090088454-A1 | ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-04-02 | — | — | US | disclosed |
| EP-2019819-A1 | NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS | Neobiotics AB (SE) | 2009-02-04 | — | — | EP | disclosed |
| US-20080255055-A1 | Use of Derivatives of Dipeptides for the Manufacture of of a Medicament for the Treamtent of Microbial Infections | NEOBIOTICS AB (SE) | 2008-10-16 | — | — | US | disclosed |
| WO-2008124756-A1 | COMPOSITIONS AND METHODS FOR TREATING BONE CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-10-16 | — | — | WO | disclosed |
| US-7427496-B2 | Anti-cancer compounds | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-09-23 | — | — | US | disclosed |
| WO-2007129952-A1 | NOVEL PEPTIDE DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS FOR TREATING WOUNDS | NEOBIOTICS AB (SE) | 2007-11-15 | — | — | WO | disclosed |
| US-20060183772-A1 | To inhibit tumor growth in an animal; to induce apoptosis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-17 | — | — | US | disclosed |
| US-20060116327-A1 | Dipeptide derivatives with active agents to formulate one composition to reduce, eliminate more than one microorganism; effect against a broad spectrum of microorganisms; mechanism of action on pathogen may be on a basic level; low probability for developing resistance | NEOBIOTICS AB (SE) | 2006-06-01 | — | — | US | disclosed |
| US-5754271-A | PHOTOCHROMIC DYES FOR SUNGLASSES AND CONTACT LENSES | ESSILOR INTERNATIONAL (COMPAGNIE GENERAL D'OPTIQUE) (FR) | 1998-05-19 | — | — | US | disclosed |
| US-4001130-A | DETERGENTS, SUBSTITUTED BUTADIENES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116327-A1 | Dipeptide derivatives with active agents to formulate one composition to reduce, eliminate more than one microorganism; effect against a broad spectrum of microorganisms; mechanism of action on pathogen may be on a basic level; low probability for developing resistance | ARG1, ARGLU1, VIP | ALDH1A1 4362/4885TRPA1 1421/4885LMNA 4296/4885 |
| US-20080255055-A1 | Use of Derivatives of Dipeptides for the Manufacture of of a Medicament for the Treamtent of Microbial Infections | VIP, ARG1, PEPD | ALDH1A1 3543/4885TRPA1 1710/4885LMNA 4687/4885 |
| US-10829464-B2 | Benzoheterocyclic alkylamine compounds and use thereof | AADAC, AAAS, NISCH | ALDH1A1 3071/4885TRPA1 732/4885LMNA 1155/4885 |
| US-20190315703-A1 | BENZOHETEROCYCLIC ALKYLAMINE COMPOUNDS AND USE THEREOF | AADAC, AAAS, NISCH | ALDH1A1 3071/4885TRPA1 732/4885LMNA 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.