SCHEMBL6016496

SCHEMBL6016496

O=CC=Cc1ccc(-c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.74
TRPA1 O75762 1/20 0.74
LMNA P02545 1/20 0.74
ALOX5 P09917 1/20 0.74
MAPK1 P28482 1/20 0.74
KDM4E B2RXH2 1/20 0.56
MAPT P10636 1/20 0.56
HDAC2 Q92769 2/20 0.50
CA1 P00915 1/20 0.50
MGLL Q99685 1/20 0.50
MAOB P27338 1/20 0.50
HDAC1 Q13547 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
TP53 P04637 1/20 0.45
XDH P47989 1/20 0.45
CDK4 P11802 3/20 0.44
CCND1 P24385 3/20 0.44
CCNB2 O95067 2/20 0.44
CDK1 P06493 2/20 0.44
CCNB1 P14635 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334479 1.00 ALDH1A1 (0.74) ALDH1A1TRPA1LMNAALOX5MAPK1
Biphenyl SCHEMBL4693704 0.93 ALDH1A1 (0.86) ALDH1A1TRPA1LMNAALOX5MAPK1
SCHEMBL14262692 0.91 ALDH1A1 (0.61) ALDH1A1TRPA1LMNAALOX5MAPK1
Cinnamaldehyde SCHEMBL28599267 0.86 ALDH1A1 (0.90) ALDH1A1TRPA1LMNAALOX5MAPK1
Cinnamaldehyde SCHEMBL25267814 0.85 ALDH1A1 (1.00) ALDH1A1TRPA1LMNAALOX5MAPK1
Cinnamaldehyde SCHEMBL3442 0.85 ALDH1A1 (1.00) ALDH1A1TRPA1LMNAALOX5MAPK1
Cinnamaldehyde SCHEMBL2203965 0.85 ALDH1A1 (1.00) ALDH1A1TRPA1LMNAALOX5MAPK1
Cinnamic Aldehyde SCHEMBL1866630 0.85 ALDH1A1 (1.00) ALDH1A1TRPA1LMNAALOX5MAPK1
Cinnamic Aldehyde SCHEMBL159856 0.85 ALDH1A1 (1.00) ALDH1A1TRPA1LMNAALOX5MAPK1
Cinnamaldehyde SCHEMBL28377500 0.85 ALDH1A1 (1.00) ALDH1A1TRPA1LMNAALOX5MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN claimed
US-20210115310-A1 ADHESION-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL PORCHER INDUSTRIES (FR) 2021-04-22 US claimed
EP-3784719-A1 ADHERENCE-IMPROVING COMPOSITION FOR TEXTILE MATERIAL AND ASSOCIATED REINFORCING TEXTILE MATERIAL Porcher Industries (FR) 2021-03-03 EP claimed
CN-112135862-A Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2020-12-25 CN claimed
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US disclosed
CN-118530156-A Synthesis method of chiral beta-substituted tryptophan derivative 大连理工大学 2024-08-23 CN disclosed
EP-4326071-A1 LIQUID REPELLENT SLIPPERY SURFACES AND METHODS OF PREPARATION THEREOF University Of Durham (GB) 2024-02-28 EP disclosed
EP-4192244-A1 MOLECULE-CONTAINING SURFACES AND METHODS OF PREPARATION THEREOF University of Durham (GB) 2023-06-14 EP disclosed
CN-114105993-B Synthesis method of chiral pyrroloimidazole compound 大连理工大学 2023-03-10 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN disclosed
US-20010021775-A1 Benzimidazolinones, benzoxazolinones, benzopiperazinones, indanones, and derivatives thereof as inhibitors of factor Xa HAN QI (US) 2001-09-13 US disclosed
US-6207697-B1 AMIDINYL-SUBSTITUTED RINGS; ANTICOAGULANTS; THROMBOEMBOLIC DISORDERS; ANTIISCHEMIC AND ANTIINFLAMMATORY AGENTS; STROKES; SERINE PROTEASE INHIBITORS DUPONT PHARMACEUTICALS COMPANY 2001-03-27 US disclosed
EP-1015429-A1 BENZIMIDAZOLINONES, BENZOXAZOLINONES, BENZOPIPERAZINONES, INDANONES, AND DERIVATIVES THEREOF AS INHIBITORS OF FACTOR XA Du Pont Pharmaceuticals Company (US) 2000-07-05 EP disclosed
WO-1999012903-A1 BENZIMIDAZOLINONES, BENZOXAZOLINONES, BENZOPIPERAZINONES, INDANONES, AND DERIVATIVES THEREOF AS INHIBITORS OF FACTOR XA DU PONT PHARMACEUTICALS COMPANY (US) 1999-03-18 WO disclosed
US-5754271-A PHOTOCHROMIC DYES FOR SUNGLASSES AND CONTACT LENSES ESSILOR INTERNATIONAL (COMPAGNIE GENERAL D'OPTIQUE) (FR) 1998-05-19 US disclosed
EP-0802897-A1 NOVEL COMPOUNDS Smithkline Beecham S.p.A. (IT) 1997-10-29 EP disclosed
WO-1996021638-A1 NOVEL COMPOUNDS SMITHKLINE BEECHAM S.P.A. (IT) 1996-07-18 WO disclosed
US-4001130-A DETERGENTS, SUBSTITUTED BUTADIENES HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010021775-A1 Benzimidazolinones, benzoxazolinones, benzopiperazinones, indanones, and derivatives thereof as inhibitors of factor Xa F12, F13B, F11 ALDH1A1 1992/4885TRPA1 2562/4885LMNA 278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.