Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 4/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711386 | 0.93 | HIF1A (0.44) | HIF1AGRIK1CMKLR1MEN1POLB | |
| SCHEMBL6709874 | 0.90 | GRIK1 (0.39) | HIF1AGRIK1MEN1KMT2ACSNK2A1 | |
| SCHEMBL6711456 | 0.88 | HIF1A (0.46) | HIF1AGRIK1MEN1POLBKMT2A | |
| SCHEMBL6708048 | 0.88 | TNIK (0.36) | HIF1APOLBF11KLKB1CSNK2A1 | |
| SCHEMBL6710483 | 0.88 | HIF1A (0.46) | HIF1AGRIK1MEN1POLBCLK1 | |
| SCHEMBL6708837 | 0.87 | KMT2A (0.41) | HIF1AGRIK1MEN1POLBCLK1 | |
| SCHEMBL6707716 | 0.86 | HIF1A (0.43) | HIF1AGRIK1ROCK1 | |
| SCHEMBL6707764 | 0.85 | HIF1A (0.41) | HIF1AMEN1POLBCLK1GFER | |
| SCHEMBL6710165 | 0.84 | ALDH1A1 (0.40) | HIF1AGRIK1CMKLR1MEN1POLB | |
| SCHEMBL6708495 | 0.84 | HIF1A (0.45) | HIF1AGRIK1F11KLKB1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | HIF1A 296/4885GRIK1 3885/4885CMKLR1 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.