Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CMKLR1 | Q99788 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711925 | 0.91 | ALDH1A1 (0.47) | ALDH1A1HIF1ALMNAMAPTHSD17B10 | |
| SCHEMBL6709013 | 0.90 | RXFP1 (0.38) | ALDH1A1HIF1ALMNARAB9AMAPT | |
| SCHEMBL6710040 | 0.88 | CSF1R (0.38) | ALDH1A1HIF1ALMNARAB9AMAPT | |
| SCHEMBL6709879 | 0.86 | HIF1A (0.48) | HIF1AGRIK1CMKLR1 | |
| SCHEMBL6710157 | 0.86 | ALDH1A1 (0.40) | ALDH1A1HIF1ANPC1LMNARAB9A | |
| SCHEMBL6708495 | 0.85 | HIF1A (0.45) | HIF1AGRIK1 | |
| SCHEMBL6709902 | 0.84 | HIF1A (0.44) | HIF1AGRIK1CMKLR1KMT2APOLB | |
| SCHEMBL6708781 | 0.84 | HIF1A (0.45) | HIF1AGRIK1KMT2APOLBMEN1 | |
| SCHEMBL6709033 | 0.84 | HIF1A (0.49) | ALDH1A1HIF1AGRIK1KMT2A | |
| SCHEMBL6711456 | 0.83 | HIF1A (0.46) | ALDH1A1HIF1ANPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ALDH1A1 123/4885HIF1A 296/4885NPC1 3891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.