Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711863 | 0.91 | GRM4 (0.37) | LMNAGRM4ROCK1RXFP1MAPT | |
| SCHEMBL6710144 | 0.90 | ROCK1 (0.39) | LMNAGRM4ROCK1RXFP1KDM4E | |
| SCHEMBL6710507 | 0.90 | HIF1A (0.42) | LMNAGRM4RXFP1POLBMAPT | |
| SCHEMBL6711785 | 0.89 | HPGD (0.40) | GRM4ROCK1POLBMAPTKDM4E | |
| SCHEMBL6711396 | 0.88 | HSD11B1 (0.38) | GRM4ROCK1RXFP1MAPTTP53 | |
| SCHEMBL6708796 | 0.88 | RXFP1 (0.39) | LMNAGRM4ROCK1RXFP1POLB | |
| SCHEMBL6710080 | 0.87 | RXFP1 (0.35) | LMNAGRM4ROCK1RXFP1MAPT | |
| SCHEMBL6708989 | 0.87 | LMNA (0.38) | LMNAGRM4POLBMAPTTP53 | |
| SCHEMBL6712526 | 0.87 | RXFP1 (0.39) | LMNAGRM4ROCK1RXFP1TP53 | |
| SCHEMBL6714173 | 0.86 | GRM4 (0.47) | LMNAGRM4ROCK1RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | LMNA 4062/4885GRM4 4668/4885ROCK1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.