Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.37 |
| ▸ | F10 | P00742 | 7/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707713 | 0.89 | HIF1A (0.41) | GRM4KDM1AROCK1F10RXFP1 | |
| SCHEMBL6713205 | 0.88 | GRM4 (0.52) | GRM4ROCK1RXFP1MAP3K5MEN1 | |
| SCHEMBL6708813 | 0.86 | TRPA1 (0.39) | GRM4KDM1AROCK1MAP3K5KMT2A | |
| SCHEMBL6708039 | 0.86 | F10 (0.40) | GRM4ROCK1F10F2MEN1 | |
| SCHEMBL6711933 | 0.85 | PTGDR2 (0.43) | GRM4KDM1AROCK1F10F2 | |
| SCHEMBL6710348 | 0.84 | ALDH1A1 (0.41) | GRM4KDM1AROCK1F10F2 | |
| SCHEMBL6710324 | 0.83 | ROCK1 (0.50) | ROCK1F10MEN1KMT2A | |
| SCHEMBL6714173 | 0.82 | GRM4 (0.47) | GRM4ROCK1RXFP1MAP3K5MEN1 | |
| SCHEMBL6710275 | 0.82 | HDAC3 (0.43) | GRM4ROCK1F10F2STK33 | |
| SCHEMBL6707974 | 0.82 | CNR2 (0.42) | GRM4ROCK1F10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRM4 4668/4885KDM1A 620/4885ROCK1 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.