Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 11/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709874 | 0.93 | GRIK1 (0.39) | GRIK1HIF1ACSNK2A1RARAROCK1 | |
| SCHEMBL6711386 | 0.90 | HIF1A (0.44) | GRIK1HIF1ACSNK2A1RARAROCK1 | |
| SCHEMBL6710116 | 0.88 | GPR27 (0.40) | GRIK1HIF1AROCK1MAPTALDH1A1 | |
| SCHEMBL6713401 | 0.87 | TNIK (0.36) | HIF1ACSNK2A1RARAROCK1TNIK | |
| SCHEMBL6707834 | 0.87 | ALDH1A1 (0.39) | GRIK1MAPTALDH1A1 | |
| SCHEMBL6708931 | 0.86 | GRIK1 (0.37) | GRIK1HIF1AROCK1 | |
| SCHEMBL6709988 | 0.85 | TNIK (0.35) | HIF1ACSNK2A1ROCK1TNIKALDH1A1 | |
| SCHEMBL6708927 | 0.85 | GRIK1 (0.41) | GRIK1HIF1AROCK1MAPT | |
| SCHEMBL6707696 | 0.84 | GRIK1 (0.40) | GRIK1HIF1AROCK1MAPT | |
| SCHEMBL6708976 | 0.84 | GRIK1 (0.51) | GRIK1HIF1AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885HIF1A 296/4885CSNK2A1 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.