Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707640 | 0.91 | HIF1A (0.40) | GRIK1HIF1ACNR2ROCK1KMT2A | |
| SCHEMBL6710358 | 0.89 | HIF1A (0.34) | HIF1ACNR2 | |
| SCHEMBL6710206 | 0.88 | MAOB (0.37) | GRIK1HIF1ASCD5 | |
| SCHEMBL6708678 | 0.88 | LRRK2 (0.39) | GRIK1HIF1A | |
| SCHEMBL6709974 | 0.87 | GPR35 (0.33) | HIF1ASCD5KMT2AMEN1GPR35 | |
| SCHEMBL6708931 | 0.85 | GRIK1 (0.37) | GRIK1HIF1AROCK1 | |
| SCHEMBL6707793 | 0.83 | HIF1A (0.45) | GRIK1HIF1AKMT2AMEN1GPR35 | |
| SCHEMBL6711803 | 0.81 | HIF1A (0.38) | GRIK1HIF1AKMT2AMEN1GPR35 | |
| SCHEMBL6711800 | 0.81 | HIF1A (0.45) | GRIK1HIF1ASCD5ROCK1KMT2A | |
| SCHEMBL6709830 | 0.81 | BRD4 (0.39) | GRIK1HIF1AROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GRIK1 3885/4885HIF1A 296/4885CNR2 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.