Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709979 | 0.89 | MAOB (0.35) | GPR35HIF1ANPSR1RXFP1SCD5 | |
| SCHEMBL6707827 | 0.89 | HIF1A (0.32) | HIF1A | |
| SCHEMBL6708058 | 0.88 | ENPP3 (0.36) | HIF1AKMT2A | |
| SCHEMBL6709047 | 0.88 | SMPD1 (0.37) | GPR35HIF1A | |
| SCHEMBL6710102 | 0.87 | GRIK1 (0.35) | GPR35HIF1ASCD5KMT2AMEN1 | |
| SCHEMBL6710115 | 0.86 | HDAC1 (0.35) | GPR35HIF1ANPSR1RXFP1 | |
| SCHEMBL6710496 | 0.83 | GPR35 (0.46) | GPR35HIF1AKMT2AMEN1 | |
| SCHEMBL6713264 | 0.82 | GPR35 (0.39) | GPR35HIF1ANPSR1RXFP1KMT2A | |
| SCHEMBL6710038 | 0.82 | HIF1A (0.45) | GPR35HIF1ANPSR1RXFP1SCD5 | |
| SCHEMBL6713076 | 0.81 | AURKA (0.35) | GPR35HIF1ANPSR1RXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | GPR35 2928/4885HIF1A 296/4885NPSR1 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.