SCHEMBL6710108

SCHEMBL6710108

O=C(Nc1cccc2cc(C(=O)Nc3ccc(Cl)cc3-c3noc(=O)[nH]3)[nH]c12)c1cccc(S(=O)(=O)N2CCOCC2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALB P02768 5/20 0.56
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
GAA P10253 4/20 0.46
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
PLK4 O00444 1/20 0.46
ROCK2 O75116 1/20 0.46
MAP4K4 O95819 1/20 0.46
PRKCG P05129 1/20 0.46
CSF1R P07333 1/20 0.46
PIM1 P11309 1/20 0.46
RPS6KB1 P23443 1/20 0.46
CDK2 P24941 1/20 0.46
FLT4 P35916 1/20 0.46
KDR P35968 1/20 0.46
FLT3 P36888 1/20 0.46
MAPK9 P45984 1/20 0.46
CSNK1A1 P48729 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6710088 0.90 ALB (0.49) ALBMEN1KMT2AGAAALDH1A1
SCHEMBL6710265 0.88 ALB (0.56) ALBMEN1KMT2AGAAALDH1A1
SCHEMBL6708577 0.86 ALB (0.54) ALBMEN1KMT2AGAAALDH1A1
SCHEMBL6710141 0.84 GRIK1 (0.44) KDM4E
SCHEMBL6707643 0.82 ALB (0.64) ALBMEN1KMT2AGAAALDH1A1
SCHEMBL6713656 0.82 GRIK1 (0.42) MEN1KMT2AALDH1A1KDM4ENPC1
SCHEMBL6709929 0.81 GRIK1 (0.49) GAAKDRL3MBTL1MAPT
SCHEMBL6713155 0.81 SERPINE1 (0.48) MEN1KMT2AKDM4ENPC1LMNA
SCHEMBL6710389 0.80 MEN1 (0.40) MEN1KMT2A
SCHEMBL2885426 0.80 KMT2A (0.59) ALBMEN1KMT2AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040142981-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142981-A1 Antibacterial benzoic acid derivatives GABRD, PHB1, GABBR1 ALB 1298/4885MEN1 4100/4885KMT2A 3181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.