Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710588 | 0.91 | TP53 (0.43) | TP53POLBMAPTLMNARXFP1 | |
| SCHEMBL6710139 | 0.89 | RXFP1 (0.45) | TP53POLBMAPTLMNARXFP1 | |
| SCHEMBL6711397 | 0.86 | TP53 (0.41) | TP53POLBMAPTLMNAGPR35 | |
| SCHEMBL6708953 | 0.85 | AKR1C2 (0.45) | TP53POLBMAPTLMNAGPR35 | |
| SCHEMBL6707650 | 0.85 | P2RX1 (0.39) | TP53POLBLMNAGPR35RXFP1 | |
| SCHEMBL6712420 | 0.84 | PARP14 (0.38) | TP53POLBMAPTLMNAGPR35 | |
| SCHEMBL6710241 | 0.84 | GPR35 (0.43) | TP53POLBMAPTLMNAGPR35 | |
| SCHEMBL6712183 | 0.84 | ALDH1A1 (0.47) | POLBMAPTLMNAGPR35RXFP1 | |
| SCHEMBL6707953 | 0.83 | MAP3K5 (0.45) | TP53POLBMAPTLMNAGPR35 | |
| SCHEMBL6711741 | 0.83 | HIF1A (0.47) | TP53MAPTGPR35RXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | TP53 2699/4885POLB 626/4885MAPT 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.