Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711455 | 0.81 | CALML3 (0.35) | NLRP3 | |
| SCHEMBL7070828 | 0.72 | HDAC1 (0.34) | — | |
| SCHEMBL6335768 | 0.71 | CALML3 (0.49) | — | |
| SCHEMBL6335770 | 0.71 | CALML3 (0.49) | — | |
| SCHEMBL6021832 | 0.70 | GRM2 (0.37) | NLRP3 | |
| SCHEMBL6021836 | 0.70 | GRM2 (0.37) | NLRP3 | |
| SCHEMBL6715644 | 0.68 | MAOA (0.34) | NLRP3 | |
| SCHEMBL6021136 | 0.65 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL6021133 | 0.65 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL6339441 | 0.60 | MAOA (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2003027083-A1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-04-03 | — | — | WO | disclosed |