Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312803 | 0.94 | MMP8 (0.62) | MMP8MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL5326604 | 0.91 | MMP8 (0.53) | MMP8MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL18946161 | 0.87 | MMP8 (0.59) | MMP8ALDH1A1TP53LDHANPY1R | |
| SCHEMBL5800254 | 0.87 | MMP8 (0.55) | MMP8ALDH1A1TP53LDHANPY1R | |
| SCHEMBL15726083 | 0.87 | MMP8 (0.49) | MMP8MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL27747 | 0.85 | MMP8 (0.58) | MMP8MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL2672619 | 0.85 | MMP8 (0.54) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL1437676 | 0.85 | MMP8 (0.54) | MMP8MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL7436472 | 0.85 | MMP8 (0.54) | MMP8MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL7260547 | 0.85 | MMP8 (0.54) | MMP8MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010116270-A1 | EP2/4 AGONISTS | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20040063729-A1 | Microbiocides | BAYER CROPSCIENCE K. K. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1345940-A2 | TRIAZOLOPYRIMIDINES | Bayer CropScience K.K. (JP) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002051845-A2 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE K.K. (DE) | 2002-07-04 | — | — | WO | disclosed |
| EP-0050671-B1 | THIAZOLO(3,2-A)PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING SAME, AND DRUG CONTAINING SAME | TEIJIN LIMITED (JP) | 1985-03-20 | — | — | EP | disclosed |
| US-4383996-A | IMMUNOREGULATOR | TEIJIN LIMITED (JP) | 1983-05-17 | — | — | US | disclosed |
| EP-0050671-A1 | THIAZOLO(3,2-a)PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING SAME, AND DRUG CONTAINING SAME | TEIJIN LIMITED (JP) | 1982-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063729-A1 | Microbiocides | FPR1, MPO, FPR2 | MMP8 155/4885MEN1 4229/4885KMT2A 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.