Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 10/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211225 | 1.00 | MDM2 (0.41) | MDM2NR3C2NR3C1CTSLMDM4 | |
| SCHEMBL6049469 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNA | |
| SCHEMBL1722361 | 0.84 | CES2 (0.45) | ALDH1A1LMNAALPGSMN1; SMN2HPGD | |
| SCHEMBL155226 | 0.81 | PKM (0.36) | ALDH1A1LMNAALPGSMN1; SMN2HPGD | |
| SCHEMBL9739531 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1865674 | 0.79 | ACACB (0.39) | MDM2ALDH1A1LMNAHPGD | |
| SCHEMBL671210 | 0.78 | PTPN11 (0.37) | NR3C2NR3C1 | |
| SCHEMBL16397433 | 0.78 | S1PR3 (0.43) | MDM2ALDH1A1 | |
| SCHEMBL10714250 | 0.75 | NR3C2 (0.37) | MDM2NR3C2NR3C1CTSLDPP4 | |
| SCHEMBL1720514 | 0.73 | LMNA (0.51) | CTSLALDH1A1LMNAALPGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684570-A | Fungicidal nitroanilides substituted pyrazoles | FMC公司 | 2024-09-24 | — | — | CN | disclosed |
| EP-4388876-A2 | FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES | FMC Corporation (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-112969688-B | Fungicidal nitroaniline-substituted pyrazoles | FMC公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-3847160-B1 | FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES | FMC CORP (US) | 2024-05-08 | — | — | EP | disclosed |
| EP-3590340-B1 | INTERMEDIATES FOR THE SYNTHESIS OF FUNGICIDAL PYRAZOLES | FMC CORP (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20230148599-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | FMC CORPORATION | 2023-05-18 | — | — | US | disclosed |
| EP-4118072-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | FMC CORPORATION (US) | 2023-01-18 | — | — | EP | disclosed |
| CN-115605461-A | Fungicidal mixtures containing pyrazole derivatives | FMC公司（US） | 2023-01-13 | — | — | CN | disclosed |
| US-20210317087-A1 | FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES | FMC CORPORATION | 2021-10-14 | — | — | US | disclosed |
| WO-2021183721-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES. | FMC CORPORATION (US) | 2021-09-16 | — | — | WO | disclosed |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2017-06-01 | — | — | US | disclosed |
| US-9596853-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | FMC CORPORATION | 2015-10-29 | — | — | US | disclosed |
| US-9107412-B2 | Fungicidal pyrazoles and their mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-18 | — | — | US | disclosed |
| EP-2611296-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130123323-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-16 | — | — | US | disclosed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012024586-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012023143-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | MDM2 3592/4885NR3C2 892/4885NR3C1 867/4885 |
| US-20150305339-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | MDM2 3592/4885NR3C2 892/4885NR3C1 867/4885 |
| US-20230148599-A1 | FUNGICIDAL MIXTURES CONTAINING PYRAZOLE DERIVATIVES | CYP1B1, CYP4B1, TH | MDM2 3026/4885NR3C2 1090/4885NR3C1 1414/4885 |
| US-20210317087-A1 | FUNGICIDAL NITROANILINO SUBSTITUTED PYRAZOLES | TH, NOX1, NOX3 | MDM2 1563/4885NR3C2 1032/4885NR3C1 1145/4885 |
| US-20130123323-A1 | FUNGICIDAL PYRAZOLES | CBR3, CYP1A1, CYP1B1 | MDM2 1510/4885NR3C2 1878/4885NR3C1 1761/4885 |
| US-20170150719-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | MDM2 3592/4885NR3C2 892/4885NR3C1 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.